Alfentanil
From Wikipedia, the free encyclopedia
Alfentanil
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Systematic (IUPAC) name | |
N-[1-[2-(4-ethyl-5-oxo-1,4-dihydrotetrazol-1-yl)ethyl]- 4-(methoxymethyl)-4-piperidyl]-N-phenyl-propanamide |
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Identifiers | |
CAS number | |
ATC code | N01 |
PubChem | |
DrugBank | |
Chemical data | |
Formula | C21H32N6O3 |
Mol. mass | 416.517 g/mol |
Physical data | |
Melt. point | 140.8 °C (285 °F) |
Pharmacokinetic data | |
Bioavailability | Not applicable |
Protein binding | 92% |
Metabolism | Hepatic |
Half life | 90–111 minutes |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | Intravenous |
Alfentanil (trade name Alfenta) is a parenteral short-acting synthetic opioid analgesic drug, used for anaesthesia in surgery. While it gives less cardiovascular complications, it tends to give stronger respiratory depression. Alfentanil is a Schedule II according to the U.S. DEA website.[1]
Alfentanil was discovered at Janssen Pharmaceutica in 1976.
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[edit] External links
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Opioids | Bezitramide, Buprenorphine, Butorphanol, Dextromoramide, Dextropropoxyphene, Diamorphine, Dihydrocodeine, Fentanyl, Hydromorphone, Ketobemidone, Methadone, Morphine, Nalbufine, Nicomorphine, Opium, Oxycodone, Papaveretum, Pethidine, Piritramide, Tramadol (see also longer list) |
Salicylic acid and derivatives | Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide -- See also: NSAIDs |
Pyrazolones | Aminophenazone, Metamizole, Phenazone |
Anilides | Paracetamol (acetaminophen), Phenacetin |
Others | Ziconotide, Tetrahydrocannabinol, Ibuprofen, Ketoprofen, Mefenamic Acid, Naproxen, Diclofenac, Flurbiprofen, Diflunisal, Fenoprofen, Indomethacin, Ketorolac, Meclofenamate, Meloxicam, Piroxicam, Tolmetin |
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Barbiturates | Hexobarbital, Methohexital, Narcobarbital, Thiopental |
Ethers | Diethyl ether,Desflurane, Enflurane, Isoflurane, Methoxyflurane, Methoxypropane, Sevoflurane, Vinyl ether |
Haloalkanes | Chloroform, Halothane, Trichloroethylene |
Opioids | Alfentanil, Anileridine, Fentanyl, Phenoperidine, Remifentanil, Sufentanil |
Others | Alfaxalone, Droperidol, Esketamine, Etomidate, Hydroxybutyric acid, Ketamine, Minaxolone, Nitrous oxide, Propanidid, Propofol, Xenon |