Adie syndrome

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Adie syndrome, also Adie's syndrome or Holmes-Adie's syndrome, is caused by damage to the postganglionic fibers of the parasympathetic innervation of the eye and characterized by a tonically dilated pupil. It most commonly affects women and is unilateral in 80% of cases. The pupil is characteristically poorly reactive to light but slowly reactive to accommodation. This clinical picture is often accompanied by signs of aberrant regeneration of these nerves and asymmetrically reduced deep tendon reflexes.

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