Acular

From Wikipedia, the free encyclopedia

Acular is the popular brand name of ketorolac tromethamine ophthalmic solution. It is used as an eye-drop painkiller for localized eye injuries, etc.

Contents 1 Manufacturers 2 See also 3 External links 4 References

[edit] Manufacturers

SYNTEX (U.S.A.) L.L.C., Palo Alto, California, U.S.A. developed ACULAR, and holds the registered trademark on that name. The brand name Acular product is manufactured and distributed by Allergan, Inc., under license from Syntex^[1].

Apotex Products Group, a Canadian manufacturer, offers generic Ketorolac tromethamine 0.5% ophthalmic solution under the name "APO-KETOROLAC"^[2] in Canada and some other countries.

Syntex and Allergan sued Apotex for patent infringement of U.S. Patent No. 5,110,493 over the generic Ketorolac tomethamine product. In May, 2005, the United States court of appeals for the Federal Circuit handed Apotex a victory, ruling that a lower court upholding the Syntex patent misapplied the rules for judging whether an invention was obvious. Allergan claims the patent is valid until 2009^[3].

[edit] See also

• Ketorolac, the non-ophthalmic variety

[edit] External links

• rxlist.com monograph on ACULAR (ketorolac tromethamine ophthalmic solution) 0.5% Sterile
• allergan.com ACULAR product information
• medicinenet.com information on ketorolac tromethamine - ophthalmic (Acular)

[edit] References

1. ^ Allergan (2006). ACULAR Ketorolac tromethamine 0.5% ophthalmic solution Product Information. Allergan web site. Allergan. Retrieved on May 8, 2006.
2. ^ Apotex Products Canada (2006-05-08). APO-KETOROLAC Product Information. Apotex Products Canada Product Catalogue. Apotex Products Canada. Retrieved on May 8, 2006.
3. ^ Albainy-Jenei, Stephen R. (May 24, 2005). Federal Circuit Reverses Allergan's Patent Validity Decision. Patent Baristas web log. Retrieved on May 8, 2006.