Acquired pure red cell aplasia
From Wikipedia, the free encyclopedia
| ICD-10 | D60. |
|---|---|
| ICD-9 | 284.8 |
| DiseasesDB | 29063 |
| eMedicine | med/1967 |
Acquired pure red cell aplasia (or PRCA) refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells.
Pure red cell aplasia is regarded as an autoimmune disease. It may also be a manifestation of thymoma. It may also be as a result of viral infections such as HIV, herpes, parvovirus B19 (Fifth disease), or hepatitis. Most cases of PRCA are considered idiopathic in that there is no discernable cause. PRCA is considered an autoimmune disease as it will respond to immunosupressant treatment such as Cyclosporin A. It has also been also been shown to respond to treatments with Rituxan.
It can be associated with the administration of erythropoietin.
[edit] Pop Culture
- In the episode of House titled Spin, Kristoffer Polaha plays a cyclist with PRCA caused by a thymoma.
[edit] See also
- Diamond-Blackfan anemia (genetic red cell aplasia)
- aplastic anemia (aplasia affecting other bone marrow cells as well)
[edit] External links
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