Acetyllysine

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6-N-acetyllysine
6-N-acetyllysine

In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.

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