User talk:81.104.26.110

From Wikipedia, the free encyclopedia

You have new messages (last change).

I will find the reference for the potency & duration. The increased duration is because the 7-8 double bond is one point at which the body metabolizes the drug. Potency is a bit harder to explain. The previous version stated it was only 1/2 the potency of morphine. I guess this is from some early German trials on animals that is now discredited. I think I'm right in saying that morphine is not used in Japan, only dihydromorphine because of it's extended duration.

The naming of ketobemidone is wrong. propionoxy would refer to a propionic acid ester when their is a propane-1-one in that position. I might not have got it QUITE right, but it's a lot closer than the current version...

It wasn't propionoxy, it was propionyl, which is correct. I have now reverted. 213.67.208.25 12:38, 3 November 2006 (UTC)

I have seen it refered to (1 oxo) propane. Is that the old naming convension. I could swear that propionyl refers to an acid substrate (well, when I google it it says so). This is a ketone... Also, couldn't both 4 substituants be refered to as 4 alpha propiophenone?

Look at the Acetyl article, propionyl is just one extra carbon. And if you don't believe me, look at this scientific article (from 1993!) where they use this exact naming: http://www3.interscience.wiley.com/cgi-bin/abstract/109568002/ABSTRACT?CRETRY=1&SRETRY=0 81.227.124.63 13:24, 5 November 2006 (UTC)

Understood!

Retrieved from "http://en.wikipedia.org../../../8/1/2E/User_talk%7E81.104.26.110.html"