3Beta Hydroxysteroid dehydrogenase

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3 β-Hydroxysteroid dehydrogenase, or 3 β-HSD is a group of steroidogenic enzymes.[1]

The main steroidogenic isoform, 3 β-HSD I, catalyzes the conversion of pregnenolone to progesterone, the conversion of 17-Hydroxypregnenolone to 17-Hydroxyprogesterone, and the conversion of DHEA to Androstenedione.

It is mainly expressed in the gonads and the adrenal cortex.

[edit] Pathway

Pathway
Pathway
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[edit] References

  1. ^ Payne AH, Abbaszade IG, Clarke TR, Bain PA, Park CH (January 1997). "The multiple murine 3 beta-hydroxysteroid dehydrogenase isoforms: structure, function, and tissue- and developmentally specific expression.". Steroids 62 (1): 169-75. PMID 9029733. Retrieved on 16 August 2006. 

[edit] External links

v • d • e
Oxidoreductases: alcohol oxidoreductases (EC 1.1)

Carbohydrate dehydrogenases - Lactate dehydrogenase - Malate dehydrogenase - Isocitrate dehydrogenase - Phosphogluconate dehydrogenase - Glucose-6-phosphate dehydrogenase

Hydroxysteroid dehydrogenase: 11 Beta (HSD11B1, HSD11B2) - 3 Beta (3-beta-HSD)

Glucose oxidase - L-gulonolactone oxidase - Xanthine oxidase

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