2C-T-2

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2C-T-2
Chemical name 2-[4-(ethylthio)-2,5-dimethoxyphenyl]ethanamine
Chemical formula C12H19NO2S
Molecular mass 241.35 g/mol
Melting point  ?
Amphetamine analog Aleph-2
CAS numbers 207740-24-7
SMILES NCCC1=C(OC)C=C(SCC)C(OC)=C1
Chemical structure of 2C-T-2

2C-T-2 is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized in 1981 by Alexander Shulgin, sometimes used as an entheogen. The drug has structural and pharmacodynamic properties similar to the drugs mescaline, MDMA, and 2C-T-7.

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[edit] Chemistry

Chemically 2C-T-2 is 4-ethylthio-2,5-dimethoxyphenethylamine, with the formula C12H19O2NS. The full chemical name is 2-[4-(ethylthio)-2,5-dimethoxyphenyl]ethanamine.

[edit] Dosage

In Shulgin's book PiHKAL (Phenethylamines I Have Known and Loved), the dosage range is listed as 12 to 25 mg. According to Erowid a threshold dose would be 5 mg, a light dose would range from 10-15 mg, a common dose is 16-32 mg and a strong dose would be considered to be 32-48 mg.

[edit] Effects

Effects are similar to the related 2C-T-7, but 2C-T-2 is said to produce more of a "body-load" and other unpleasant reactions with reported reddening of the face and warm flushes. However, there have been no reported deaths from 2C-T-2, unlike 2C-T-7, and the psychedelic effects have been much milder. Effects can last between six and eight hours.

[edit] Pharmacology

The mechanism that produces 2C-T-2’s hallucinogenic and entheogenic effects has not been specifically established, however it is most likely to result from action as a 5-HT2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.

[edit] Dangers

The toxicity of 2C-T-2 is not well documented. 2C-T-2 is considerably less potent than 2C-T-7, but it may be expected that at higher doses it would display similar toxicity to that of other phenethylamines of the 2C-T family. Other phenethylamine derivatives substituted with an alkylthio group at the 4 position such as 2C-T-7 and 4-MTA are known to act as selective monoamine oxidase A inhibitors, a side effect which can lead to lethal serotonin syndrome when they are combined with stimulant drugs. Most confirmed fatalities involving 2C-T drugs involve their combination with other hard drugs such as alcohol, ecstasy or cocaine.

[edit] Law

2C-T-2 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-2 will probably be prosecuted under the Federal Analog Act because of its structural similarities to 2C-T-7.

2C-T-2 and all other compounds featuring in PiHKAL are illegal drugs in the United Kingdom.

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