2-Aminoisobutyric acid

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2-Aminoisobutyric acid
Systematic (IUPAC) name
Alpha-Aminoisobutyric acid
Identifiers
CAS number 62-57-7
ATC code  ?
PubChem 6119
DrugBank EXPT00471
Chemical data
Formula C4H9NO2 
Mol. mass 103.121 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

2-Aminoisobutyric acid, or α-aminoisobutyric acid (AIB) or α-methylalanine or 2-methylalanine, is an amino acid with the structural formula is H2N-C(CH3)2-COOH.

It is contained in some antibiotics of fungal origin, eg. alamethicin and some lantibiotics. It is not one of the proteinogenic amino acids and rather rare in nature.

α-Aminoisobutyric acid is a strong helix inducer in peptides. Its oligomers form 3-10 helices.

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