Wilson Greatbatch

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Wilson Greatbatch (born September 6, 1919) is an inventor who advanced the development of early implantable cardiac pacemakers. He is a graduate of Cornell University and the University at Buffalo. Greatbatch is often miscredited as the inventor of the pacemaker as a whole.

1 The Chardack-Greatbatch pacemaker
2 The Greatbatch lithium-iodide battery cell
3 See also
4 External links

[edit] The Chardack-Greatbatch pacemaker

The earliest known creation of an implantable pacemaker was by Åke Senning and Rune Elmquist of Sweden in 1958. Greatbatch improved upon the two men's earlier work by creating the Chardack-Greatbatch pacemaker in 1960. It used Mallory mercuric oxide-zinc cells for its energy source, driving a two transistor, transformer coupled blocking-oscillator circuit, all encapsulated in epoxy resin, then coupled to electrodes placed into the myocardium of the patient's heart. The main difference between this pacemaker and the Swedish one is the battery technology used. This patented innovation led to the Medtronic company of Minneapolis commencing manufacture and further development of cardiac pacemakers.

[edit] The Greatbatch lithium-iodide battery cell

In 1968, Catalyst Research Corporation of Baltimore, Maryland developed and patented a lithium-iodide battery cell. The cell used two elements at near ends of the electrochemical scale, causing a high voltage of 2.8V and an energy density near the physical maximum. Unfortunately, it had an internal impedance which limited it's current load to under 0.1 mA and was thus considered useless.

Greatbatch sought to introduce this invention into the pacemaker industry, which could readily utilize a high impedance battery. The early work was conducted in a rented area of the derelict Wurlitzer Organ Factory in Buffalo, New York. Ralph Mead is understood to have headed the early electrochemical development.

Greatbatch introduced the developed WG1 cell to pacemaker developers in 1971, and was met with limited enthusiasm. The lithium-iodide cell manufactured by WG is now the standard cell for pacemakers, having the energy density, low self-discharge, small size and reliability needed.

In the cell as developed for cardiac pacemaker application, the anode is lithium and the cathode a proprietary composition of iodine and poly-2-vinyl pyridine, neither of which is electrically conductive, however after processing by mixing and heating to ~ 150 °C for 72 hours the components react with each other to form an electrically conductive viscous paste which, while still molten, is poured into the cell where it cools to form a solid. When the paste contacts the lithium anode it creates a monomolecular layer of semiconducting crystalline lithium iodide. As the cell is discharged by the current load of the pacemaker, the reaction between the lithium anode and iodine cathode forms a growing barrier of lithium iodide, which being resistive causes the terminal voltage of the cell to decrease approximately as an inverse function of the volume of the barrier. Pacemaker designers use this characteristic to permit detection of incipient 'end of life' of the pacemaker's lithium cell.