Wikipedia:WikiProject Molecular and Cellular Biology/Collaboration of the Month

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RNA interference
This month's MCB Collaboration of the Month article is RNA interference.
Please help to improve this article to featured article status.
Last month's collaboration was proteasome

The Article Creation and Improvement Drive is a monthly collaboration to improve molecular and cellular biology articles to good or featured article status.

/History - For past winners.
/Removed - For removed nominations.

Contents

[edit] Introduction

To vote or nominate you have to be a registered user with at least one contribution that is not a vote. Any molecular and cellular biology related article may be nominated except:

A great place to start is the project worklist, which contains a list of many articles that have been identified as being of interest to the project, as well as their importance and state of completion.

[edit] How to nominate

I
Add nomination

Copy and paste the following template to the bottom of the list of nominations on this page and fill it out.

===[[Article]]===
{{MCB CoM|start=December 15, 2006|votes=1}}

; Support:
# ~~~~

; Comments:
* (put your reason for nomination) ~~~~

Under "comments" section put an explanation of what work is needed.

II
Notify

After submitting the new nomination, go to the nominated article and put

{{MCBnom}}{{to do}}

on the top of the article's talk page. (skip {{to do}} if it's already present on the articles talk page)

[edit] How to vote

Sign with "# ~~~~" on the end of the list of the article you want to vote for and then update the vote count in the template. You can vote for as many articles as you like.

[edit] How the article is selected

Article with most votes on the first day of each month in 00:00 GMT is selected as "The current MCB Article Improvement Drive article". If two articles have same number of votes, the older nominee wins.

Comment The next selection will be on Monday, 01 January 2007 00:00:00 (UTC)

[edit] How an article is removed from the list

Articles need one vote per two weeks to stay on the list. If the current date (December 15, 2006) exceeds the "stays until" date of that particular article, the article entry is removed from this page and moved to page for removed nominations.

[edit] Nominations

[edit] Peripheral membrane protein

8 votes. Nominated September 7, 2006; needs at least 9 votes by December 28, 2006
Support
  1. Xcomradex 12:18, 6 September 2006 (UTC)
  2. Reo ON | +++ 12:40, 6 September 2006 (UTC) Exactly! I wanted nominate just membrane protein myself, but I restrained from this, because it is so far from the state of good article, that we can hardly reach it. (but I prefer rather such focus over the goal of shaping articles in the fase of good articles, while I believe we have hardly power to make good article within article drive from this substrat)
  3. Adenosine | Talk 16:30, 12 September 2006 (UTC) | "Membrane proteins are so important and so under studied, under appreciated, misunderstood, etc"
  4. ClockworkSoul 23:35, 17 October 2006 (UTC) Good idea... this looks like it'll be our topic in November.
  5. M&NCenarius 17:51, 1 November 2006 (UTC)
  6. JE.at.UWOU|T 18:34, 11 November 2006 (UTC) Great idea. It needs A LOT of work, but there is a lot of information here to work with. I look forward to collaborating on this with all of you. I'm new to wikipedia and this is a first for me!
  7. Yes, I think this is a great idea! If this article is selected for collaboration, I will work more to improve it. Right now I am trying to prepare a paper about peripheral membrane proteins, but this is only a very small part of the story. Biophys 21:03, 15 November 2006 (UTC)
  8. Opabinia regalis 03:31, 30 November 2006 (UTC)
Comments
  • The whole membrane protein area needs work, integral membrane protein is the most complete, but membrane protein and peripheral membrane protein are a bit woeful. perhaps some talented wikiartists could whip up a few diagrams? it could be a co-project with Adenosine triphosphate, given that articles completeness? Xcomradex 12:18, 6 September 2006 (UTC)
    • If you should find any other articles like these that clearly deserve the attention of the MCB WIkigroup, tag them with the {{Wikiproject MCB}} template on their talk page. Full details on how to use it are on the project worklist page. – ClockworkSoul 13:04, 6 September 2006 (UTC)
      • The list of peripheral proteins (even those with known 3D structures) is extremely incomplete, and a lot more can be said about these proteins in general. One way to proceed might be to look for information about membrane-associated proteins in public databases, such as TransportDB, localization databases, or UniProt (any other ideas?). Another option is to identify different specific sub-classes of peripheral proteins (or different subjects - I could suggest some and recommend reveiw papers), and everyone could select his favorite part to work with. Biophys 21:03, 15 November 2006 (UTC)
      • There are no articles about membrane-targeting domains (C1, C2, PX, etc.) in Wikipedia. This is a big gap. There are no articles about protein-lipid interactions. Biophys 21:57, 15 November 2006 (UTC)

[edit] Citric acid cycle

6 votes. Nominated September 27, 2006; needs at least 7 votes by December 20, 2006
Support
  1. ClockworkSoul 04:14, 27 September 2006 (UTC)
  2. Opabinia regalis 04:51, 27 September 2006 (UTC)
  3. GAThrawn22 01:05, 18 October 2006 (UTC)
  4. Adenosine | Talk 04:42, 18 October 2006 (UTC) | I worked on this early, oops! I have already designed a new diagram! but it could still use work.
  5. M&NCenarius 17:51, 1 November 2006 (UTC)
  6. Mr.Bip 05:57, 6 November 2006 (UTC)
Comments
  • This article is in very sorry shape. It needs some serious work before it's anything more than an eyesore.
    This is a sorry mess. I'm actually very surprised at how bad this is. Opabinia regalis 04:51, 27 September 2006 (UTC)
  • Perhaps this could be coordinated with Wikiproject Metabolic Pathways. ShaiM 09:06, 18 October 2006 (UTC)
  • This is about as basic of a topic as you get. Mr.Bip 05:57, 6 November 2006 (UTC)

[edit] Cell membrane

4 votes. Nominated October 17, 2006; needs at least 5 votes by December 12, 2006 Overdue
Support
  1. ClockworkSoul 23:04, 17 October 2006 (UTC)
  2. Reo ON | +++ 17:36, 22 October 2006 (UTC)
  3. Opabinia regalis 02:04, 26 October 2006 (UTC)
  4. M&NCenarius 17:48, 1 November 2006 (UTC)
Comments
  • This subject, one of the fundamental topics in cell biology, is in sorry shape. This could easily be brought to featured status with just a little attention from our combined knowledge. – ClockworkSoul 23:04, 17 October 2006 (UTC)

[edit] Cell metabolism

4 votes. Nominated October 20, 2006; needs at least 5 votes by December 15, 2006
Support
  1. ClockworkSoul 19:07, 20 October 2006 (UTC)
  2. Opabinia regalis 02:04, 26 October 2006 (UTC)
  3. M&NCenarius 17:48, 1 November 2006 (UTC)
  4. Keesiewonder 20:59, 1 December 2006 (UTC)
Comments
  • For such a central subject this article is so bad that I would think it's a satire if I didn't know better. The main image actually has little pictures of chicken and cheese pointing into a cell to represent catabolism. This must be fixed! – ClockworkSoul 19:07, 20 October 2006 (UTC)
You have a knack for finding the really abominable ones :) Opabinia regalis 02:04, 26 October 2006 (UTC)
Oh, it's no so hard... I just go through our worklist and pick out some of the red or orange ones. – ClockworkSoul 16:27, 29 October 2006 (UTC)

[edit] Topoisomerase

3 votes. Nominated November 12, 2006; needs at least 4 votes by December 24, 2006
Support
  1. SenorKristobbal 16:17, 12 November 2006 (UTC)
  2. ClockworkSoul 18:34, 15 November 2006 (UTC)
  3. Opabinia regalis 03:31, 30 November 2006 (UTC)
Comments
  • Topoisomerases are vital for cell replication. Every organism has at least 2 and they are currently being looked at for bacterial and cancer treatments. SenorKristobbal 16:17, 12 November 2006 (UTC)

[edit] Hemoglobin

3 votes. Nominated November 15, 2006; needs at least 4 votes by December 27, 2006
Support
  1. ClockworkSoul 18:34, 15 November 2006 (UTC)
  2. Keesiewonder 13:06, 27 November 2006 (UTC)
  3. Opabinia regalis 00:09, 11 December 2006 (UTC)
Comments
  • A very high-profile topic, and a subject of close study for nearly all undergraduate students in biology and biochemistry. It's already in pretty good shape, and with a bit of polishing, I think that we can get it up to a full FA status. – ClockworkSoul 18:34, 15 November 2006 (UTC)
  • Excellent suggestion! I was just reading/writing about this material yesterday. Keesiewonder 13:09, 27 November 2006 (UTC)

[edit] T-DNA

2 votes. Nominated November 16, 2006; needs at least 3 votes by December 14, 2006 Overdue
Support
  1. Reo ON | +++ 12:33, 16 November 2006 (UTC)
  2. Keesiewonder 13:07, 27 November 2006 (UTC)
Comments
  • The topic is absolutely missing, there is nothing except the redirect to Agrobacterium tumefaciens. Even there is virtually no condensed information about the T-DNA.

[edit] RNA polymerase

3 votes. Nominated November 30, 2006; needs at least 4 votes by January 11, 2007
Support
  1. Opabinia regalis 03:37, 30 November 2006 (UTC)
  2. ClockworkSoul 06:44, 30 November 2006 (UTC)
  3. Keesiewonder 11:01, 30 November 2006 (UTC)
Comments
  • Hope no one minds a repeat nomination :) I didn't see this one last time and would absolutely have supported, and as the subject of the chemistry Nobel this should be better than it is. Opabinia regalis 03:37, 30 November 2006 (UTC)
  • Couldn't agree more. It's a shame I've been in the lab every night until midnight, because I sure would love to help on this too. – ClockworkSoul 06:44, 30 November 2006 (UTC)

[edit] Signal transduction

6 votes. Nominated December 2, 2006; needs at least 7 votes by February 24, 2007
Support
  1. Opabinia regalis 07:53, 2 December 2006 (UTC)
  2. Reo ON | +++ 12:30, 4 December 2006 (UTC)
  3. Dr Aaron 12:54, 6 December 2006 (UTC)
  4. ClockworkSoul 14:27, 6 December 2006 (UTC)
  5. Lord Metroid 17:47, 6 December 2006 (UTC)
Comments
  • This is about four articles in one. Content itself doesn't look so bad at first glance, but it's unreferenced, over-sectioned, and unnecessarily lengthy while still covering each individual subtopic incompletely. Based on the history, it's gone relatively unmaintained and has been subject to slow edit creep for a long time. Opabinia regalis 07:53, 2 December 2006 (UTC)
  • I don't vote often, but I really agree that this would be one that could benefit from a major reworking! Dr Aaron 12:54, 6 December 2006 (UTC)
  • This article is horrible, while not of the highest importance. Hemoglobine is already nice, we should try to lift the standards in general rather than trying to achieve FA status on articles when there is lousy articles still left. Lord Metroid 17:47, 6 December 2006 (UTC)

[edit] Thymocyte

3 votes. Nominated December 10, 2006; needs at least 4 votes by January 21, 2007
Support
  1. Sad mouse 23:57, 10 December 2006 (UTC)
  2. ClockworkSoul 06:48, 11 December 2006 (UTC)
  3. Opabinia regalis 06:55, 11 December 2006 (UTC)
Comments
  • T cells are essential for immunity against pathogens and cancer, and drive autoimmunity. Yet absolutely nothing was written about the development of T cells in the thymocyte article. I spent quite a while writing the article, but it would be great to get others to help on it to make this essential immunology topic a featured article. Sad mouse 23:57, 10 December 2006 (UTC)
  • Also, most of the collaborations so far have been molecular, so it would be nice to have a cellular topic. Sad mouse 01:44, 11 December 2006 (UTC)