Wikipedia:WikiProject Cell Signaling
From Wikipedia, the free encyclopedia
Some Wikipedians have formed a project to better organize information in articles related to Cell Signaling. This page and its subpages contain their suggestions; it is hoped that this project will help to focus the efforts of other Wikipedians. If you would like to help, please inquire on the talk page and see the to-do list there.
For more information on WikiProjects, please see Wikipedia:WikiProject and Wikipedia:WikiProject/Best practices.
Contents |
[edit] Title
WikiProject on Cell Signaling
[edit] Scope
This project is dedicated to improving and organising the Wikipedia articles on cell signaling to provide a convinient and reliable reference of the known signal transduction pathways. It covers the pathway pages and individual protein pages related to them.
[edit] Goals
- Creating comprehensive articles for each known cell signaling pathway
- Organising cell signaling articles with navigation boxes like these: Wikipedia:WikiProject Molecular and Cellular Biology#Protein topics navigation boxes.
- Organising and creating articles on notable proteins involved in signaling pathways.
- Providing each pathway with a clear diagram of its structure.
- Clearly citing sources, especially for active research topics
[edit] Target audience
- Introduction to pathway articles should be make minimal use of jargon and be kept relatively simple
- Subsections and protein pages can be more technical
[edit] Parentage
This is a daughter project of WikiProject Molecular and Cellular Biology
[edit] Similar WikiProjects
WikiProject Clinical medicine and WikiProject Drugs may be relevant to this project.
[edit] Participants
| Name | Talk page | Special interests |
|---|---|---|
| Peter Znamenskiy | Talk | Cell culture and adult stem cells |
| Rockpocket | Talk | G-protein coupled receptors |
| David Iberri | Talk | Embryogenesis (especially nervous system development) |
| John Schmidt | Talk | illustrations |
| Gacggt | Talk | Skeletal Muscle biology, Akt pathway, NF-kappaB pathway, some GPCRs, Neurotrophins, MuSK, agrin, Neuromuscular junction, etc |
| Kohlasz | Talk | Chemotaxis |
| EquationDoc | Talk | Pathways involved in cancer prevention and formation |
| JE.at.UWO | Talk | Immunology, development, endocrinology and reproductive physiology. |
[edit] Structure
Proposed structure of a pathway article:
- General introduction - keep it simple and clear
- History/Discovery - discovery, seminal papers
- Mechanism - the proteins involved and how they interact.
- Role - the role of the pathway
- Human disease - alternatively this can be incorporated into the previous section
- Current research - recent advances, future directions
For individual proteins, see suggestions in Wikipedia:WikiProject_Molecular_and_Cellular_Biology#Structures
Proposed scheme for pathway diagrams is described here. Please do comment and contribute.
[edit] Hierarchy definition
No classification of this project has been defined.
[edit] Projects
[edit] Tasks
- Complete - build a sample pathway article: Hedgehog signaling pathway
- Complete - resolve the Cell signaling/Signal transduction merger, no merge
- Compile list of existing cell signaling articles - please add articles to the list below
- Design a convention for drawing pathway diagrams
[edit] Adopt an article
Similar to the Collaboration of the week, but on a smaller scale, you might want to "adopt" an article. This would involve doing the research, writing, and picture-taking (if possible) for either a non-existent article or a stub. Of course, everyone else can still edit an adopted article, and you can work on other things too, but the idea is to find a focus for a while, to try and build up the number of quality articles the Project has produced.
- Example article: User:Example
[edit] General strategy and discussion forums
- /General
- /Strategy
[edit] Templates
[edit] Infoboxes
[edit] Other templates
{{Template:Cell Signaling Project}}
 |
This article is part of WikiProject Cell Signaling, an attempt to better organise information in articles related to cell signaling and signal transduction. If you would like to participate, you can edit the article attached to this page, or visit the Cell Signaling WikiProject project, where you can join the project and/or contribute to the discussion. |
| Cell signaling |
|---|
| Key concepts - Ligand | Receptor | Second messenger | Protein kinase | Transcription factor | Cell signaling networks |
| Pathways - Apoptosis | Ca2+ signaling | Cytokine signaling | Hedgehog | Integrin signaling | JAK/STAT | Lipid signaling | MAPK/ERK pathway | mTOR | NF-kB | Notch | p53 | TGFβ | Wnt |
| Lipid signaling |
|---|
| Phospholipase | Phosphatidylinositol (4,5)-bisphosphate | Diacylglycerol | Inositol triphosphate | Inositol triphosphate receptor |
{{Template:TGF beta signaling}}
| TGF beta signaling pathwayedit | |
|---|---|
| TGF beta superfamily of ligands: | |
| Activin A | Activin B | Anti-müllerian hormone | BMP2 | BMP3 | BMP4 | BMP5 | BMP6 | BMP7 | BMP8a | BMP8b | BMP10| BMP15 | GDF1 | GDF2 | GDF3 | GDF5 | GDF6 | GDF7 | GDF9 | GDF10 | GDF11 | GDF15| Inhibin A | Inhibin B | Myostatin | Nodal | TGFβ1 | TGFβ2 | TGFβ3 | |
| Type II receptors: ACVR2A | ACVR2B | AMHR2 | BMPR2 | TGFBR2 | TGFBR3 | |
| Type I receptors: ACVR1A | ACVR1B | ACVR1C | ACVRL1 | BMPR1A | BMPR1B | TGFBR1 | |
| Signal transducers: SMAD1 | SMAD2 | SMAD3 | SMAD4 | SMAD5 | SMAD6 | SMAD7 | SMAD9 | |
| Ligand Inhibitors: Cerberus | Chordin | DAN | Decorin | Follistatin | Gremlin | Lefty | LTBP1 | Noggin | THBS1 | |
| Coreceptors: BAMBI | Cripto Other: SARA |
[edit] Categories
[edit] Lists
[edit] Articles
[edit] Archives
- #1
[edit] Sister Project links
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