Walter Dobrogosz
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Walter Dobrogosz is a Professor Emeritus of North Carolina State University, most well-known for his discovery and further research on the probiotic bacterium Lactobacillus reuteri.
Dobrogosz was born in 1933 in Albion, Pennsylvania. He grew up in Erie, Pennsylvania, and received his B.S., Masters, and Ph. D. degrees from Penn State University. He married in 1953, and is the father of four children, including musician Steve Dobrogosz. He completed a postdoctoral fellowship at the University of Illinois, and afterwards began teaching at N.C. State University, where he remained until his retirement in 2003.
During his time at N.C. State, Dobrogosz discovered L. reuteri, a new lactic acid bacterium. Dobrogosz and his fellows obtained a patent on the bacterium and on the anti-microbial agent it produces, termed reuterin, and later began to market L. reuteri for its benefits to human and animal health; L. reuteri has been shown to maintain intestinal health, prevent fungal, bacterial, and protozoal infections, and mediate the body's immune response. The company marketing L. reuteri has grown and is now known as Biogaia.
Dobrogosz now lives in Raleigh, North Carolina.
Sources: http://microbiology.ncsu.edu/WJD/WJD.html
[edit] Selected Publications
Ivan A. Casas, Walter J. Dobrogosz. "Validation of the Probiotic Concept: Lactobacillus reuteri Confers Broad-spectrum Protection against Disease in Humans and Animals," Microbial Ecology in Health and Disease, December 1 2000, Volume 12, Number 4. (link to article)
Edens FW, Parkhurst CR, Casas IA, Dobrogosz WJ "Principles of ex ovo competitive exclusion and in ovo administration of Lactobacillus reuteri," Poult Science, January 1997 Entrez PubMed 9037704
Lindgren SE, Dobrogosz WJ. "Antagonistic activities of lactic acid bacteria in food and feed fermentations," FEMS Microbiol Review, September 1990. Entrez PubMed 2125429
Talarico TL, Dobrogosz WJ. "Chemical characterization of an antimicrobial substance produced by Lactobacillus reuteri," Antimicrobial Agents and Chemotherapy, May 1989, Volume 33, Number 5. Entrez PubMed 2751282
Talarico TL, Casas IA, Chung TC, Dobrogosz WJ. "Production and isolation of reuterin, a growth inhibitor produced by Lactobacillus reuteri," Antimicrobial Agents and Chemotherapy, December 1988, Volume 32, Number 12. Entrez PubMed 3245697
Lee JH, Dobrogosz WJ. "Effects of aerobic and anaerobic shock on catabolite repression in cyclic AMP suppressor mutants of Escherichia coli," Journal of Bacteriology, May 1983, Volume 154, Number 2. Entrez PubMed 6302089
