Vanillyl mandelic acid

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Vanillyl mandelic acid (VMA) is a chemical end product of catecholamine metabolism. It is found in urine together with homovanillic acid (HVA). In timed urine tests its quantity (concentration μg /24 h) is assessed, along with creatinine clearance, and the concentration of cortisols, catecholamines, and metanephrines.

Urinary levels of vanillyl mandelic acid are raised in pheochromocytoma, a tumor of catecholamine-secreting chromaffin cells.

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