Tropicamide

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Tropicamide chemical structure
Tropicamide
Systematic (IUPAC) name
N-ethyl-3-hydroxy-2-phenyl-N- (pyridin-4-ylmethyl) propanamide
Identifiers
CAS number 1508-75-4
ATC code S01FA06
PubChem 5593
DrugBank APRD00287
Chemical data
Formula C17H20N2O2
Mol. weight 284.353 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 45%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Tropicamide (troe-PIK-a-mide) is an acetylcholine receptor blocker, (a muscarinic antagonist). It is used to dilate (enlarge) the eye's pupil in order to allow better examination of the lens, vitreous humor, and retina. It is typically used during eye examinations, but may also be used before or after eye surgery.

Application of tropicamide can produce short acting mydriasis and cycloplegia.

Tropicamide is occasionally administered in eye drops in combination with hydroxyamphetamine (brand name Paremyd®) to dilate the pupil.

Anisocoria. Right eye was instiled by tropicamide
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Anisocoria. Right eye was instiled by tropicamide
Right eye half an hour after administration of tropicamide
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Right eye half an hour after administration of tropicamide


[edit] See also