Trimethadione

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Trimethadione chemical structure
Trimethadione
Systematic (IUPAC) name
3,5,5-trimethyloxazolidine-2,4-dione
Identifiers
CAS number 127-48-0
ATC code N03AC02
PubChem 5576
DrugBank APRD00315
Chemical data
Formula C6H9NO3 
Mol. weight 143.141
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Prescription only

Routes  ?

Trimethadione is an oxazolidinedione anticonvulsant. It is used to treat epileptic conditions that are resistant to other treatments.

It can be associated with fetal trimethadione syndrome.

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Anticonvulsants (N03) edit

Barbiturates: Barbexaclone, Metharbital, Methylphenobarbital, Phenobarbital, Primidone

Hydantoins: Ethotoin, Fosphenytoin, Mephenytoin, Phenytoin

Oxazolidinediones: Ethadione, Paramethadione, Trimethadione

Succinimides: Ethosuximide, Mesuximide, Phensuximide

Benzodiazepines: Clobazam, Clonazepam, Clorazepate, Diazepam, Lorazepam, Midazolam, Nitrazepam, Temazepam

Carboxamides: Carbamazepine, Oxcarbazepine, Rufinamide Fatty acid derivatives: Valpromide, Valnoctamide

Carboxylic acids: Valproic acid (Sodium valproate & Valproate semisodium), Tiagabine -- GABA analogs: Gabapentin, Pregabalin, Progabide, Vigabatrin

Others:- Monosaccharides: Topiramate -- Aromatic allylic alcohols: Stiripentol -- Ureas: Phenacemide, Pheneturide -- Phenyltriazines: Lamotrigine

Carbamates: Emylcamate, Felbamate, Meprobamate -- Pyrrolidines: Brivaracetam, Levetiracetam, Nefiracetam, Seletracetam

Sulfa drugs: Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide

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