Trifluperidol

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Trifluperidol (1-(4-fluorophenyl)-4-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidyl]butan-1-one , C22H23F4NO2) is a butyrophenone with general properties similar to those of Haloperidol. It is used in the treatment of psychoses including mania and schizophrenia. Trifluperidol was discovered at Janssen Pharmaceutica in 1959.

[edit] References

  • Gallant DM, Bishop MP, Timmons E, Steele CA, A controlled evaluation of Trifluperidol: a new potent psychopharmacologic agent, Curr Ther Res Clin Exp. 1963 Sep;27:463-71.
  • Gallant DM, Bishop MP, Timmons E, Steele CA, Trifluperidol: a butyrophenone derivative, Am J Psychiatry. 1963 Nov;120:485-7.


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