Trephine

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A trephine with a center pin can be seen on the left.
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A trephine with a center pin can be seen on the left.

A trephine (/ˌtɹɪˈfiːn/) is a surgical instrument. It has a cylindrical blade and is used for harvesting of bone plugs, cutting holes in bones (i.e. the skull) or for cutting out a round piece of the cornea for eye surgery. A bone marrow trephine shows the pattern of the marrow as it lies in the bone, undisturbed.

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