Traumatic acid
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| Traumatic acid | |
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| Systematic name | Dodec-2-enedioic acid |
| Chemical formula | C12H20O4 |
| Molecular mass | 228.285 g/mol |
| Density | x.xxx g/cm3 |
| Melting point | 165.5°C |
| Boiling point | xx.x °C |
| CAS number | 6402-36-4 |
| SMILES | C(CCCCC(=O)O)CCCC=CC(=O)O |
| Disclaimer and references | |
Traumatic acid is a monounsaturated dicarboxylic acid naturally ocurring in plants. The compound was first isolated from wounded bean plants by American chemists James English Jr. and James Frederick Bonner and Dutch scientist Aire Jan Haagen-Smit in 1939. Traumatic acid is a potent wound healing agent in plants ("wound hormone") that stimulates cell division near a trauma site to form a protective callus and to heal the damaged tissue. It may also act as a growth hormone, especially in inferior plants (e.g. algae). Traumatic acid is biosynthesized in plants by non-enzimatic oxidation of traumatin (12-oxo-trans-10-dodecanoic acid), another wound hormone.
At normal conditions, traumatic acid is a solid, crystalized, water insoluble substance.
Traumatic acid is used as an intermediate in prostaglandin synthesis. It is also a constituent of some pharmaceutical products, such as odontostomatologic gel Restomyl® due to its mucosal re-epithelialization activity.
