Tomosyn
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In biology, tomosyn is a protein with approximately 1,100 amino acids. It has two functional domains, one of which binds to syntaxin. Dybbs et al. used positional cloning to show that tomosyn inhibits neurotransmitter secretion in neurons.
[edit] References
- Dybbs M, Ngai J, Kaplan JM (2005) Using Microarrays to Facilitate Positional Cloning: Identification of Tomosyn as an Inhibitor of Neurosecretion. PLoS Genet 1(1): e2
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