Tolfenamic acid

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Tolfenamic acid
Systematic (IUPAC) name
2-[(4-chloro-3-methyl-phenyl)amino]benzoic acid
Identifiers
CAS number	13710-19-5
ATC code	?
PubChem	5507
Chemical data
Formula	C14H12ClNO2
Mol. weight	261.707
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	oral

Tolfenamic acid (TA) is one of the class of non steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.

Contents 1 Other possible uses 2 Commercial names 3 External links 4 References

[edit] Other possible uses

• A study concludes, "TA was found significantly better than placebo in the subjective evaluation of drug efficacy (p<0.001) and in reducing the reported hangover symptoms in general (p < 0.01). In the TA group, significantly lower symptom scores were obtained for headache (p<0.01), and for nausea, vomiting, irritation, tremor, thirst and dryness of mouth (all p < 0.05)."^[1]

[edit] Commercial names

Commercial names for tolfenamic acid include:

• Clotam® Rapid

[edit] External links

• Tolfenamic acid information

[edit] References

1. ^ S. Kaivola1, J. Parantainen, T. Österman and H. Timonen Hangover headache and prostaglandins: Prophylactic treatment with tolfenamic acid Cephalalgia Volume 3 Page 31 - March 1983 doi:10.1046/j.1468-2982.1983.0301031.x

Non-steroidal anti-inflammatory drugs (primarily M01A and M02A, also N02BA) edit

Salicylates: Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide -- Arylalkanoic acids: Diclofenac, Indometacin, Sulindac 2-Arylpropionic acids (profens): Carprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Ketorolac, Loxoprofen, Naproxen, Tiaprofenic acid, N-Arylanthranilic acids (fenamic acids): Mefenamic acid -- Pyrazolidine derivatives: Phenylbutazone Oxicams: Meloxicam, Piroxicam -- Coxibs: Celecoxib, Etoricoxib, Parecoxib, Rofecoxib, Valdecoxib -- Sulphonanilides: Nimesulide Topically used products: Diclofenac, Flurbiprofen, Ibuprofen, Indometacin, Ketoprofen, Naproxen, Piroxicam