Tinidazole

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Image:Tinidazole.png

Tinidazole
Systematic (IUPAC) name
1-(2-ethylsulfonylethyl)-2-methyl-5-nitro-imidazole
Identifiers
CAS number	19387-91-8
ATC code	J01 XD02 P01 AB02
PubChem	5479
DrugBank	APRD01260
Chemical data
Formula	C₈H₁₃N₃O₄S
Mol. weight	247.273 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Tinidazole is an anti-parasitic drug used against protozoan infections. It is widely known throughout Europe and the Third World as treatment for a variety of amoebic and parasitic infections. It is chemically similar to Metronidazole — a drug with some unpleasant side effects that is used in the United States as first-line therapy for amoebae. Tinidazole has similar side effects but you don't have take it as long.

Tinidazole is marketed by Mission Pharmacal under the brand name Tindamax®.

Tinidazole is FDA approved for the treatment of trichomoniasis, giardiasis and amebiasis. A large body of clinical data exists to support its use as a treatment for amoebae, giardia and vaginal trichomona, just like metronidazole. Tinidazole may be a therapeutic alternative in the setting of metronidazole intolerance.

[edit] Side Effects

The most common side effects reported with tinidazole are upset stomach, bitter taste, and itchiness. Other side effects which occur are headache, fatigue, and dizziness. But these studies weren't performed in people with AIDS. Anecdotally, people who have taken both Flagyl and tinidazole report toxicity is much the same except the side effects don't last as long. Note: drinking alcohol while taking tinidazole will make you violently ill.