Tibotec
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Tibotec is a pharmaceutical company with a focus on research and development for the treatment of infectious diseases such as HIV (AIDS), and Hepatitis C. The company develops antiretroviral drugs for the treatment of AIDS.
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[edit] History
In 1994, Rudi Pauwels (Rega Institute for Medical Research) founds Tibotec, together with is wife Carine Claeys, and Marie-Pierre de Béthune, Kurt Hertogs, and Hilde Azijn. In 1995 Paul Stoffels (Janssen Pharmaceutica) joins Tibotec. Tibotec was acquired by Johnson & Johnson in April 2002. The name of the company is derived from the tetrahydro-imidazo[4,5,1-jk][1,4]-benzodiazepine-2(1H)-one and -thione (TIBO) compounds discovered at the Rega Institute for Medical Research (Belgium)[1].
[edit] Drugs
- TMC114 (darunavir), a protease inhibitor (PI), (recently approved by the FDA)
- TMC125, (etravirine) a non-nucleoside reverse transcriptase inhibitor (NNRTI),
- TMC278, (rilpivirine) a NNRTI.
Tibotec licensed TMC120, a NNRTI, to the International Partnership for Microbicides for its development as a vaginal microbicide in March 2004.
[edit] References
- ^ Pauwels R, Andries K, Desmyter J, Schols D, Kukla MJ, Breslin HJ, Raeymaeckers A, Van Gelder J, Woestenborghs R, Heykants J, et al., Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives, Nature. 1990 Feb 1;343(6257):470-4
[edit] See also
[edit] External links
| Johnson & Johnson | |
|---|---|
| William C. Weldon, Chairman & CEO,Robert J. Darretta, Jr., Vice Chairman & CFO, | |
| Past CEOs and Presidents: Robert Wood Johnson I • James Wood Johnson • Robert Wood Johnson II • Robert Wood Johnson III • Philip B. Hofmann • Richard B. Sellars • James E. Burke • Ralph S. Larsen | |
| Selected Subsidiaries | |
| ALZA Corporation • Cilag • DePuy, Inc. • Ethicon Endo-Surgery, Inc. • Ethicon, Inc. • Independence Technology, LLC • Janssen Pharmaceutica • McNeil Consumer & Specialty Pharmaceuticals • Ortho-McNeil Pharmaceutical • Ortho-Neutrogena • Penaten • Tibotec | |
| Selected Brands | |
| Acuvue • Aveeno • Band-Aid • Carefree • Clean & Clear • Johnson's Baby • K-Y • Neutrogena • Rembrandt • Stayfree • Tylenol | |
Annual Revenue: $10.411 billion USD (FY 2005) | Employees: 116,200 | Stock Symbol: NYSE: JNJ | Website: www.jnj.com |
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