Thermus thermophilus

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iThermus thermophilus
Scientific classification
Kingdom: Bacteria Phylum: Deinococcus-Thermus Class: Deinococci Order: Thermales Family: Thermaceae Genus: Thermus Species: T. thermophilus
Binomial name
Thermus thermophilus

Thermus thermophilus is a gram negative eubacterium used in a range of biotechnological applications, including as a model organism for genetic manipulation and systems biology. The bacterium is extremely thermophilic, with an optimal growth temperature of about 85ºC. Thermus thermophilus was originally isolated from a thermal vent environment in Japan. T. thermophilus is classified into several strains, in which HB8 and HB27 are most common and their genome analyses were independently completed in 2004.

[edit] Biotechnological applications of Thermus thermophilus enzymes

• rTth DNA polymerase is a recombinant thermostable DNA polymerase derived from Thermus thermophilus, with optimal activity at 70-80ºC, used in some PCR applications. The enzyme possesses efficient reverse transcriptase activity in the presence of manganese.

[edit] External links

• Thermus thermophilus HB27 genome page.
• Thermus thermophilus HB8 genome page.
• Structural-biological whole cell project of Thermus thermophilus HB8.