Terlipressin
From Wikipedia, the free encyclopedia
| Image:Terlipressin.png | |
|
Terlipressin
|
|
| Systematic (IUPAC) name | |
| ? | |
| Identifiers | |
| CAS number | ? |
| ATC code | H01BA04 |
| PubChem | 72081 |
| DrugBank | EXPT03310 |
| Chemical data | |
| Formula | C52H74N16O15S2 |
| Mol. weight | 1227.37 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | ~30% |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | IV |
Terlipressin as vasoactive drug used for the management of hypotension. It has been found to be effective when norepinephrine does not help.
Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used in bleeding esophageal varices.
[edit] See also
[edit] References
- ↑ O'Brien A, Clapp L, Singer M. Terlipressin for norepinephrine-resistant septic shock. Lancet. 2002 Apr 6;359(9313):1209-10. PMID 11955542.
- ↑ Uriz J, Gines P, Cardenas A, Sort P, Jimenez W, Salmeron JM, Bataller R, Mas A, Navasa M, Arroyo V, Rodes J. Terlipressin plus albumin infusion: an effective and safe therapy of hepatorenal syndrome. J Hepatol. 2000 Jul;33(1):43-8. Full Text. PMID 10905585.
- ↑ Ioannou G, Doust J, Rockey DC. Terlipressin for acute esophageal variceal hemorrhage. Cochrane Database Syst Rev 2003;(1):CD002147. PMID 12535432.
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
