Suppository
From Wikipedia, the free encyclopedia
A suppository is a medicine that is inserted either into the rectum (rectal suppository), vagina (vaginal suppository) or urethra (urethral suppository) where it dissolves. The alternative term for delivery of medicine via such routes, is as a pharmaceutical pessary.
Vaginal suppositories are used to treat gynaecological ailments, especially vaginal infections such as candidiasis, or as vaginal contraceptives.
Rectal suppositories are used:
- For laxative purposes, with chemicals such as glycerin or bisacodyl.
- To treat a hemorrhoid by delivering a moisturizer or vasoconstrictor.
- For general medical administration purposes: the substance crosses the rectal mucosa into the bloodstream; examples include paracetamol (acetaminophen) and eucalyptol suppositories.
Alprostadil pellets are urethral suppositories used for the treatment of severe erectile dysfunction. They are marketed under the name Muse in the United States.[1] Its use has diminished since the development of oral impotence medications, but is still on the market.
Except for glycerin suppositories, suppositories are made of a greasy excipient (formerly, cocoa butter) in which the active substance is diluted. This may be a source of discomfort for the patient, as the melted excipient may pass the anus during flatulences.
Suppositories are used especially for small child patients, for they may be easier to administer than tablets or syrups.
