Sulfamethizole
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Sulfamethizole
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| Systematic (IUPAC) name | |
| 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)- benzenesulfonamide | |
| Identifiers | |
| CAS number | 144-82-1 |
| ATC code | B05CA04 D06BA04, J01EB02, S01AB01 |
| PubChem | 5328 |
| DrugBank | APRD00684 |
| Chemical data | |
| Formula | C9H10N4O2S2 |
| Mol. weight | 270.333 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 98–99% |
| Metabolism | ? |
| Half life | 3–8 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Sulfamethizole is a sulfonamide antibiotic.
[edit] External links
- Ratanajamit C, Skriver M, Nørgaard M, Jepsen P, Schønheyder H, Sørensen H (2003). "Adverse pregnancy outcome in users of sulfamethizole during pregnancy: a population-based observational study.". J Antimicrob Chemother 52 (5): 837-41. PMID 14519675.
- Kerrn M, Frimodt-Møller N, Espersen F (2003). "Effects of sulfamethizole and amdinocillin against Escherichia coli strains (with various susceptibilities) in an ascending urinary tract infection mouse model.". Antimicrob Agents Chemother 47 (3): 1002-9. PMID 12604534.
- Watanabe H, Hastings J (1990). "Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine.". Biochim Biophys Acta 1017 (3): 229-34. PMID 2372557.
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| Sulfonamides (J01E) edit | ||
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Mafenide, Prontosil, Sulfacetamide, Sulfamethizole, Sulfamethoxazole (with Trimethoprim in Co-trimoxazole), Sulfanilimide, Sulfasalazine, Sulfisoxazole |
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