User:Stone/Flouride
From Wikipedia, the free encyclopedia
Fluorides are organic and inorganic compounds containing the element fluorine.
[edit] Inorganic Fluorides
As a halogen, fluorine forms a monovalent ion (charge -1). Examples of common fluoride compounds include hydrofluoric acid (HF), calcium fluoride (CaF2)and sodium fluoride (NaF).
A fluoride ion is the ionic form of fluorine. Fluorides are the salts of hydrofluoric acid. As fluorine is a highly reactiv element fluorine is found only as fluoride ion in salts. The minerals cryolithe, fluorapatite topaz and chiolith and fluorspar which is the starting material for all other fluorine containing materials. As part of the Period 2 element the possibility of multiple oxidation states for fluorine is limited to the -1 the oxidation state in fuorides. As the most electronegative element with the highest electron afinity of -3.448. The fluoride ion is the smalest negatively charged ion with a radius of 1.33 Angstrom.
[edit] Organic Fluorides
The organic fluorides have unique properties.
The space filling of the fluorine and a hydrogen differ far less than with all other possible substituents.
Substitution of one hydrogen with fluorine or a CH3 group by a CF3 group is often tested in development of pharmacutical molecules the change in pharmacokinetics and necessary dosage are changed in a positive way.
Perfluorinated hydrocarbons built a third phase lipophile and hydrophil .
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