User:Steinsky/todo

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HIV protease in a complex with the protease inhibitor ritonavir

Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Inhibitor binding is either reversible or irreversible. Irreversible inhibitors usually react with the enzyme and change it chemically. These inhibitors modify key amino acid residues needed for enzymatic activity. In contrast, reversible inhibitors bind non-covalently and different types of inhibition are produced depending on whether these inhibitors bind the enzyme, the enzyme-substrate complex, or both. Their discovery and improvement is an active area of research in biochemistry and pharmacology. A medicinal enzyme inhibitor is often judged by its specificity (its lack of binding to other proteins) and its potency (its dissociation constant, which indicates the concentration needed to inhibit the enzyme). A high specificity and potency ensure that a drug will have few side effects and thus low toxicity. Enzyme inhibitors also occur naturally and are involved in the regulation of metabolism. (more...)

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Petrified wood

Petrified wood
Photo credit: Daniel Schwen
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The current UK Collaboration of the Fortnight is British-Spanish relations.
Every fortnight a different UK-related topic, stub or non-existent article is picked.
Please read the nomination text and improve the article any way you can.
The current UK geography collaboration of the month is Rutland.

If you see ways in which this article can be improved please edit it. You may get ideas from the talk page or the WikiProject UK geography.

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The Lizard, Stourhead, Marram grass, Coastal defenses, landform, coast, Dingle Peninsula, Glastonbury, Bristol city centre, Hampshire, Blandford Forum, Bournemouth, Dorchester, Gillingham, Lyme Regis, Sherborne, Shaftesbury, Upwey, Weymouth, Bridport, Abbotsbury, Cerne Abbas, Corfe Castle, Corfe Mullen, Kimmeridge, Melbury Abbas, Milton Abbas, Poole, Stalbridge, Sturminster Newton, Studland, Swanage, Wimborne Minster, Bridgwater, Chew Stoke, Frome, North Petherton, Montacute, Nether Stowey, South Cadbury, Street, Wellington, Pilton, Tyneham, Wareham, Badbury Rings, Pentridge, Cheddar, Ashmore, Minehead, Affpuddle, Cranborne, Tolpuddle, Dulverton, Crewkerne, pentose phosphate pathway

Stubs: sea wall, beach nourishment, raised beach, Alderholt, Allington, Alton Pancras, Arne, Askerwell, Batcombe, Beaminster, Beer Hackett, Bere Regis, Bettiscombe, Bincombe, Bishops Caundle, , Bloxworth, Bothenhampton, Bourton, Bradford Abbas, Bradford Peverell, Bradpole, Broadmayne, Broadwey, Broadwindsor, Bryanston, Buckhorn Weston, Buckland Newton, Buckland Ripers, Burstock, Burton Bradstock, Cann, Castleton, Cattistock, Caundle Marsh, Chalbury, Chaldon Herring, Charlestown, Charlton Marshall, Charminster, Charmouth, Chedington, Cheselbourne, Chetnole, Chettle, Chickerell, Chideock, Child Okeford, Christchurch, Church Knowle, Clifton Maybank, Colehill, Compton Abbas, Compton Valence, Coombe Keynes, Corscombe, Crossways, Dewlish, Durweston, East Lulworth, East Orchard, East Stoke, East Stour, Easton, Edmondsham, Evershot, Farnham, Ferndown, Fifehead Magdalen, Fifehead Neville, Fleet, Folke, Fontmell Magna, Fortuneswell, Frampton, Frome St Quintin, Frome Vauchurch, Glanvilles Wootton, Godmanstone, Gussage, Halstock, Hermitage, Hilfield, Hilton, Hinton Martell, Hinton Parva, Hinton St Mary, Holnest, Holt, Holwell, Horton, Hurn, Ibberton, Iwerne Courtney, Iwerne Minster, Kington Magna, Langton Herring, Langton Matravers, Leigh, Lillington, Littlebredy, Littlemoor, Litton Cheney, Loders, Long Bredy, Long Crichel, Longburton, Lydlinch, Lytchett Matravers, Lytchett Minster, Maiden Newton, Manston, Mappowder, Marnhull, Marshwood, Melbury Bubb, Melbury Osmond, Melcombe Horsey, Melcombe Regis, Milborne St Andrew, Minterne Magna, Moor Crichel, Morden, Moreton, Motcombe, Mosterton, Netherbury, Nether Compton, Oborne, Okeford Fitzpane, Osmington, Over Compton, Overcombe, Owermoigne, Pamphill, Piddlehinton, Piddletrenthide, Pimperne, Portesham, Powerstock, Poyntington, Preston, Puddletown, Pulham, Puncknowle, Purse Caundle, Rampisham, Ryme Intrinseca, Sandford Orcas, Seaborough, Shapwick, Shillingstone, Shipton Gorge, Silton, Sixpenny Handley, South Perrott, Spetisbury, St Ives, St Leonards, Stanton St Gabriel, Steeple, Stinsford, Stoke Abbott, Stour Provost, Stour Row, Stourpaine, Stourton Caundle, Stratton, Sturminster Marshall, Sutton Waldron, Swyre, Sydling St Nicholas, Symondsbury, Tarrant Gunville, Tarrant Hinton, Tarrant Kayneston, Tarrant Launceston, Tarrant Monkton, Tarrant Rushton, Thorncombe, Thornford, Tincleton, Todber, Toller Porcorum, Trent, Turners Puddle, Turnworth, Upton, Verwood, Warmwell, West Knighton, West Lulworth, West Moors, West Parley, West Stafford, West Stour, Whitechurch Canonicorum, Wimborne St Giles, Winfrith Newburgh, Winterborne Houghton, Winterborne Kingston, Winterborne St Martin, Winterborne Monkton, Winterborne Stickland, Winterborne Whitechurch, Winterborne Zelston, Winterbourne Abbas, Winterbourne Steepleton, Witchampton, Woodlands, Woodsford, Wool, Woolland, Wootton Fitzpaine Worth Matravers, Wyke Regis, Yetminster, Alcombe, Alford, Ashcott, Ashill, Athelney, Axbridge, Barrington, Buckland Dinham, Burnham-on-Sea, Castle Cary, Chapel Allerton, Chew Magna, Coleford, Combe Florey, Cossington, Creech St Michael, Cudworth, Dunster, East Coker, Edington, Ilchester, Ilminster, Martock, Merriott, Porlock, Shapwick, Tolland, Walton, Watchet, Wincanton, Westbury, Wareham Forest, Abbas Combe, Cadbury Castle, Dancing Ledge, FAD

Redlinks: Portland Bill, Lulworth crumple, Lulworth Castle, Old Wardour Castle, rocky shore, limestone folding, storm beach, slumping, sub-aerial processes, through flow, overland flow, managed retreat, rock apron, rock island, Duncliffe, Bulbarrow Hill, Jordan Hill Roman Temple, Osmington Mills, Warbarrow Bay, Sherborne House, Abbotsbury Swannery, codon use bias, Hooke, Dorset, Adsborough, Alhampton, Alford, Angersleigh, Ansford, Appley, Ash, Somerset, Ash Priors, Ashbrittle, Ashington, Ashwick, Babcary, Badgworth, Baltonsborough, Barwick, Bathealton, Bawdrip, Beckington, Beercrocombe, Berkley, Somerset, Berrow, Bickenhall, Bicknoller, Binegar, Bishops Hull, Bishops Lydeard, Blue Anchor Bradford on Tone, Bratton Seymour, Brean, Brent Knoll, Brewham, Broadway, Brompton Ralph, Brompton Regis, Broomfield, Brushford, Bruton, Brympton, Buckland St Mary, Burrowbridge, Burtle, Butleigh, Cannington, Carhampton, Catcott, Chaffcombe, Charlton Horethorne, Charlton Mackrell, Charlton Musgrove, Cheddon Fitzpaine, Chedzoy, Chillington, Chilthorne Domer, Chilton Cantelo, Chilton Poldon, Chilton Trinity, Chinnock, Chipstable, Chiselborough, Churchstanton, Closworth, Combe St Nicholas, Comeytrowe, Compton Bishop, Compton Dundon, Compton Pauncefoot, Corfe, Corton Denham, Cothelstone, Cricket St Thomas, Croscombe, Crowcombe, Cucklington, Curland, Curry Mallet, Curry Rivel, Cutcombe, Dean, Dinnington, Ditcheat, Donniford, Donyatt, Doulting, Dowlish Wake, Downhead, Drayton, Durleigh, Durston, East Brent, East Chinnock, East Huntspill, East Pennard, East Quantoxhead, Easton, Elworthy, Emborough, Enmore, Evercreech, Exford, Fiddington, Fitzhead, Fivehead, Forton, Fulford, Goathurst, Godney, Great Elm, Greinton, Halse, Hambridge, Hardington Mandeville, Haselbury Plucknett, Hatch Beauchamp, Hemington, Henley, Henstridge, High Ham, Highbridge, Hinton St George, Holcombe, Holford, Holton, Horsington, Horton, Huish Champflower, Huish Episcopi, Hurst, Ilton, Isle Abbots, Isle Brewers, Keinton Mandeville, Kilmersdon, Kilve, Kingsbridge, Kingsbury Episcopi, Kingsdon, Kingston St Mary, Kingstone, Kingweston, Knowle St Giles, Lamyat, Langford Budville, Laverton, Leigh-on-Mendip, Limington, Litton, Long Load, Long Sutton, Lopen, Luccombe, Lullington, Luxborough, Lydeard St Lawrence, Lydford-on-Fosse, Lympsham, Lyng, Maperton, Mark, Marston Magna, Maundown, Meare, Mells, Middlezoy, Milborne Port, Milton Clevedon, Misterton, Monksilver, Moorlinch, Muchelney, Mudford, Nettlecombe, North Barrow, North Cadbury, North Cheriton, North Curry, North Perrott, North Wootton, Norton Fitzwarren, Norton St Phillip, North Sub Hamdon, Nunney, Nynehead, Oake, Odcombe, Old Cleeve, Orchard Portman, Othery, Otterford, Otterhampton, Over Stowey, Pawlett, Penselwood, Pitcombe, Pitminster, Pitney, Priddy, Puckington, Puriton, Pylle, Queen Camel, Rimpton, Rode, Rodney Stoke, Ruishton, Sampford Arundel, Sampford Brett, Seavington St Mary, Seavington St Michael, Selwood, Selworthy, Sharpham, Shepton Beauchamp, Shepton Montague, Shipham, Skilgate, South Barrow, South Petherton, Sparkford, Spaxton, Staple Fitzpaine, Staplegrove, Stawell, Somerset, Stawley, Stockland Bristol, Stocklinch, Stogumber, Stogursey, Stoke St Gregory, Stoke St Hampton, Stoke St Mary, Stoke Sub Hambdon, Stoke Trister, Ston Easton, Stratton-on-the-Fosse, Stringston, Tatworth,, Tellisford, Thornfalcon, Thurloxton, Timberscombe, Tintinhull, Treborough, Trudoxhill, Trull, Upton, Upton Noble, Wambrook, Wanstrow, Washford, Weare, West Bagborough, West Bradley, West Buckland, West Hatch, West Monkton, West Pennard, West Quantoxhead, Westonzoyland, Whatley, Williton, Witham Friary, Withycombe, Withypool, Wiveliscombe, Wookey, Wootton Courtenay

UK geography to do list
Bring to featured quality Stubs Requested articles
  • Crockham Hill
  • Darby Green
  • Durrington, West Sussex
  • Geography of Northern Ireland
  • Geology of England
  • Geology of Wales
  • Geology of Ireland
  • Geology of Northern Ireland
  • Geology of London
  • Lindford
  • River Ely
edit watch

[edit] UK Wikipedians' To Do list

To create

To find images

Stubs

On Featured article candidates

On Featured list candidates

/Complete to do list

To improve

On Expansion requests

On Peer Review

Nominated for deletion

(See also WikiProject Deletion sorting/UK)
WikiProject Countering systemic bias open tasks
This project creates and improves neglected articles.