Spectinomycin

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Spectinomycin chemical structure
Spectinomycin
Systematic (IUPAC) name
(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)
decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one
Identifiers
CAS number 1695-77-8
ATC code J01XX04
PubChem 15541
DrugBank APRD01232
Chemical data
Formula C14H24N2O7 
Mol. weight 332.35 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Spectinomycin (marketed as the hydrochloride salt spectinomycin hydrochloride under the trade name Trobicin®) is an aminocyclitol antibiotic produced by the bacterium Streptomyces spectabilis. It binds to the 30S ribosomal subunit in invading bacteria and interrupts protein synthesis. It is given by injection to treat gonorrhea. Side effects include itching, chills, and red rash.


Antibiotics (J01) edit


Tetracyclines (J01AA) edit

Chlortetracycline, Demeclocycline, Doxycycline, Lymecycline, Minocycline, Oxytetracycline, Tetracycline
Penicillins (J01C) edit

Amoxicillin, Ampicillin, Azlocillin, Carbenicillin, Cloxacillin, Dicloxacillin, Flucloxacillin, Mezlocillin, Nafcillin, Piperacillin, Pivampicillin, Ticarcillin


Cephalosporin Antibiotics (J01D) edit
First Generation:

Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole
Second Generation:

Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam
Third Generation:

Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef
Fourth Generation:

Cefclidine, Cefepime, Cefetecol, Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome


Sulfonamides (J01E) edit

Mafenide, Prontosil, Sulfacetamide, Sulfamethizole, Sulfamethoxazole (with Trimethoprim in Co-trimoxazole), Sulfanilimide, Sulfasalazine, Sulfisoxazole


Glycopeptides (J01, and others) edit

Macrolides: Azithromycin, Clarithromycin, Dirithromycin, Erythromycin, Roxithromycin

Others: Aztreonam, Monobactam, Teicoplanin, Vancomycin


Aminoglycosides (J01G) edit

Amikacin, Gentamicin, Kanamycin, Neomycin, Netilmicin, Streptomycin, Tobramycin, Paromomycin, Hygromycin, spectinomycin


Quinolones (J01M) edit
Fluoroquinolones:

Ciprofloxacin, Enoxacin, Fleroxacin, Gatifloxacin, Gemifloxacin, Grepafloxacin, Levofloxacin, Lomefloxacin, Moxifloxacin, Norfloxacin, Ofloxacin, Pefloxacin, Prulifloxacin, Rufloxacin, Sparfloxacin, Temafloxacin, Trovafloxacin, Sitafloxacin
Other quinolones:

Cinoxacin, Flumequine, Nalidixic acid, Oxolinic acid, Pipemidic acid, Piromidic acid, Rosoxacin


Polypeptides Antibiotics (J01XB, and others) edit

Bacitracin, Colistin, Hitachimycin, Polymyxin B


Other Antibiotics edit

Chloramphenicol, Clindamycin, Dalfopristin, Ethambutol, Fosfomycin, Furazolidone, Isoniazid, Linezolid, Metronidazole, Nitrofurantoin, Pyrazinamide, Quinupristin, Rifampin
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