Talk:Simvastatin

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Tabutterick 17:27, 7 October 2006 (UTC)—From website: By 1976, Akira Endo had isolated the first inhibitor (compactin) from yeast cultures in Sankyo, Japan. Correction needed:

Akira Endo had isolated the first inhibitor (compactin ML-236B) from the fungus, Penicillium citrinium in Sankyo, Japan. ref: Liao and Laufs, 2005. Pleiotropic Effects of Statins. Annu. Rev. Pharmacol.Toxicol:45:89-118


Pen. is not a yeast but a filamentous fungi. Since you listed the organism that sim. was isolated from you might want to include the name of this organism too.

Thank you for your time and I hope this is helpful. Tammy Butterick Third yr. Graduate Student UMN-Twin Cities Dept of Pharmacology butte017@umn.edu

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