Semicarbazone
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In organic chemistry, semicarbazone is a derivative of semicarbazide which contains an additional ketone functional group. Their structure is R2C=NNHC(=O)NH2. A 'thiosemicarbazone' contains an sulfur thio atom (sulfur) in lieu of the ketonic oygen. Both semicarbazones and thiosemicarbazones are known to have anti-viral and anti-cancer activity, usually mediated through binding to copper or iron in cells.
[edit] External links
- Overview at uni.edu
- Diagram at uic.edu
- "Kinetic vs. Equilibrium Control in Semicarbazone Formation", at msu.edu
- Description of derivatives at dcccd.edu
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