Seborrheic keratoses

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Seborrheic keratosis consists of benign, verrucous (wart-like), often pigmented, greasy lesions consisting of proliferating epidermal cells which usually occur after the third decade.

Leser-Trelat sign, the explosive onset of multiple pruritic seborrheic keratoses, often with an inflammatory base, can be an ominous sign of internal malignancy.