Rathke's pouch

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Rathke's pouch
Sketches in profile of two stages in the development of the human digestive tube.
Gray's subject #275 1277
Carnegie stage 10
Gives rise to anterior pituitary
Dorlands/Elsevier p_31/12662673

In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane. The pouch eventually loses its connection with the pharynx giving rise to the anterior pituitary. The anterior wall of Rathke's pouch proliferates, filling most of the pouch to form pars distalis and pars tuberalis. The posterior wall forms pars intermedia.

In some organisms (humans being a notable exception), the proliferating anterior wall does not fully occupy Rathke's pouch, leaving a remnant (Rathke's cleft) between the pars distalis and pars intermedia. Rathke's pouch may also persist as cysts (Rathke's cysts) within the pars intermedia.

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Mammalian development of embryo and development and fetus (some dates are approximate - see Carnegie stages) - edit - discuss

Week 1: Zygote | Morula | Blastula/Blastomere/Blastosphere | Archenteron/Primitive streak | Blastopore | Allantois | Trophoblast (Cytotrophoblast | Syncytiotrophoblast | Gestational sac)

Week 2: Yolk sac | Vitelline duct | Bilaminar disc

Week 3: Hensen's node | Gastrula/Gastrulation | Trilaminar embryo Branchial arch (1st) | Branchial pouch | Meckel's cartilage | Somite/Somitomere | Germ layer (Ectoderm, Endoderm, Mesoderm, Chordamesoderm, Paraxial mesoderm, Intermediate mesoderm, Lateral plate mesoderm)

Histogenesis and Organogenesis

Circulatory system: Primitive atrium | Primitive ventricle | Bulbus cordis | Truncus arteriosus | Ostium primum | Foramen ovale | Ductus venosus | Ductus arteriosus | Aortic arches | Septum primum | Septum secundum | Cardinal veins

Nervous system: Neural development/Neurulation | Neurula | Neural folds | Neural groove | Neural tube | Neural crest | Neuromere (Rhombomere) | Notochord | Optic vesicles | Optic stalk | Optic cup

Digestive system: Foregut | Midgut | Hindgut | Proctodeum | Rathke's pouch | Septum transversum

Urinary/Reproductive system: Urogenital folds | Urethral groove | Urogenital sinus | Kidney development (Pronephros | Mesonephros | Ureteric bud | Metanephric blastema) | Fetal genital development (Wolffian duct | Müllerian duct | Gubernaculum | Labioscrotal folds)

Glands: Thyroglossal duct

Uterine support: Placenta | Umbilical cord (Umbilical artery, Umbilical vein, Wharton's jelly) | Amniotic sac (Amnion, Chorion)

Limb development: Limb bud | Apical Ectodermal Ridge/AER