Talk:Pyruvate dehydrogenase complex

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at http://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb1/part2/krebs.htm "Pyruvate Dehydrogenase is a large complex, with multiple copies of each of three enzymes, E1, E2, and E3. The structure of the complex is depicted in figures on p. 769 & 774 of Biochemistry, 3rd Edition, by Voet & Voet. The core of the complex consists of 60 copies of E2. At the periphery of the complex are:

  • 30 copies of E1 (itself a tetramer with subunits a2b2) and
  • 12 copies of E3 (a homodimer), plus 12 copies of an E3 binding protein that links E3 to E2."

This conflicts with the article.GangofOne 07:07, 11 May 2005 (UTC)

  • EC number 1.2.4.1 is also a pyruvate dehydrogenase.


What about the influence of hormones like vasopressin and insulin on this reaction?Ankmin 03:22, 22 April 2006 (UTC))

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