Prilocaine
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Prilocaine
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Systematic (IUPAC) name | |
N-(2-methylphenyl)-2-propylamino-propanamide | |
Identifiers | |
CAS number | 721-50-6 |
ATC code | N01BB04 |
PubChem | 4906 |
DrugBank | APRD00180 |
Chemical data | |
Formula | C13H20N2O |
Mol. weight | 220.311 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Protein binding | 98% |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | ? |
Prilocaine (IPA: [ˈpraɪlokeɪn]) is a local anesthetic of the amino amide type. In its injectable form (Citanest®), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA). As it has low cardiac toxicity, it is commoly used for intravenous regional anaesthesia (IVRA).
In some patients, a metabolite of prilocaine may cause the unusual side-effect of methaemoglobinaemia.