Prilocaine

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Prilocaine chemical structure
Prilocaine
Systematic (IUPAC) name
N-(2-methylphenyl)-2-propylamino-propanamide
Identifiers
CAS number 721-50-6
ATC code N01BB04
PubChem 4906
DrugBank APRD00180
Chemical data
Formula C13H20N2O
Mol. weight 220.311 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 98%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Prilocaine (IPA: [ˈpraɪlokeɪn]) is a local anesthetic of the amino amide type. In its injectable form (Citanest®), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA). As it has low cardiac toxicity, it is commoly used for intravenous regional anaesthesia (IVRA).

In some patients, a metabolite of prilocaine may cause the unusual side-effect of methaemoglobinaemia.


Local anesthetics (N01B) edit

Articaine, Benzocaine, Bupivacaine, Chloroprocaine, Cocaine, Etidocaine, Hexylcaine, Lidocaine, Levobupivacaine, Lidocaine/prilocaine, Mepivacaine, Prilocaine, Procaine, Ropivacaine, Tetracaine

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