Platelet alpha-granule
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In platelets, the term "alpha granules" is used to describe granules containing several growth factors (such as insulin-like growth factor 1, platelet-derived growth factor, TGFβ), platelet factor 4 which is a heparin-binding chemokine, and other clotting proteins (such as thrombospondin and fibronectin.) The alpha granules express the adhesion molecule P-selectin. The other type of granules within platlets are called a dense bodies also known as delta granules.
A deficiency of alpha granules is known as grey platelet syndrome.
[edit] See also
[edit] External links
- Harrison P, Cramer E (1993). "Platelet alpha-granules.". Blood Rev 7 (1): 52-62. PMID 8467233.
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