Phosphocreatine

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Phosphocreatine, also known as creatine phosphate or PCr, is a phosphorylated creatine molecule that is an important energy store in skeletal muscle. It is used to generate ATP from ADP, forming creatine for the 2 to 7 seconds following an intense effort. This reaction is reversible and it therefore acts as a spatial and temporal buffer of ATP concentration. Phosphocreatine plays a particularly important role in tissues that have high, fluctuating energy demands such as muscle and brain. Creatine phosphate is synthesized in the liver, and transported to the muscle cells for storage.

[edit] References:

Schlattner, U., Tokarska-Schlattner, M., Wallimann, T. (2005). Mitochondrial creatine kinase in human health and disease. Biochemica et Biophysica Acta .27. (Published ahead of print).


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