Phosphatidylinositol

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Phosphatidylinositol (abbreviated PtdIns, or PI) is a minor phospholipid component of eukaryotic cell membranes. Phosphatidylinositol is a class of phospholipid, which is made up of glycerol, fatty acid and the base is replaced by a hexahydric alcohol namely inositol. This hexahydric alcohol exists as its stereoisomer - myo-inositol. Upon hydrolysis, they yield 1 mole of glycerol, 2 moles of fatty acid, 1 mole of inositol and 1,2, or 3 moles of phosphoric acids. They are regarded to be the most acidic of all the phospholipids. It is however the substrate for a large number of enzymes which are involved in cell signalling.

[edit] See also

Phosphatidylinositol 3-phosphate

Phosphatidylinositol 4-phosphate

Phosphatidylinositol 5-phosphate

Phosphatidylinositol (3,4)-bisphosphate

Phosphatidylinositol (3,5)-bisphosphate

Phosphatidylinositol (4,5)-bisphosphate

Phosphatidylinositol (3,4,5)-trisphosphate

PI 3-kinase

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