Phenazone
From Wikipedia, the free encyclopedia
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Phenazone
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| Systematic (IUPAC) name | |
| 1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one | |
| Identifiers | |
| CAS number | 60-80-0 |
| ATC code | N02BB01 |
| PubChem | 2206 |
| Chemical data | |
| Formula | C11H12N2O |
| Mol. weight | 188.226 |
| SMILES | CN(C(C)=CC2=O) N2C1=CC=CC=C1 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Phenazone, or phenazon, is an analgesic. It is formed by reducing diortho-dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 C. It crystallizes in needles which melt at 156 C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid. Phenazone is an isomer of phenazine.
Contents |
[edit] Synonyms
Analgesine, Antipyrine, Diméthyloxyquinazine, Oxydiméthylquinazine, Oxydiméthylquinizine, Pyrazoline
[edit] See also
[edit] Chimic Class
- Pyrazole
- Pyrazolinone
[edit] Pharmacology
[edit] Adverse effects
- Allergy to pyrazolones
- Nausea
- Agranulocytose
[edit] External links
| Analgesics (N02A, N02B) edit | |
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| Opioids: |
6-methylene-dihydromorphine, Acedicon, Acetorphine, Acetyldihydrocodeine, Acetyldihydrocodeinone, Acetylmorphone, Alfentanil, Allylprodine, Alphaprodine, Anileridine, Bemidone, Benzylmorphine, Betmeprodine, Betaprodine, Bezitramide, Buprenorphine, Butorphanol, Carfentanil, Clonitazene, Codeine-N-Oxide, Codeine, Codeineone, Cyclazocine, Cyclorphan, Desomorphine, Dextromethorphan, Dextropropoxyphene, Dextromoramide, Dezocine, Diacetyldihydromorphine, Diethylthiambutene, Difenoxin, Dihydromorphine, Dihydrocodeine, Dihydrocodeine enol acetate, Dihydroetorphine, Dihydroisocodeine, Dimethylthiambutene, Diphenoxylate, Dipipanone, Ethylketocyclazocine, Ethylmorphine, Etonitazene, Etorphine, Fentanyl, Diamorphine (Heroin), Hydromorphone, Hydrocodone, Isomethadone, Ketobemidone, Laudanum, Lefetamine, Levallorphan, Levo-alphacetylmethadol, Levomethadone, Levomethorphan, Levorphanol, Loperamide, Meptazinol, Metazocine, MPPP, Methadone, Methyldihydromorphine, Metopon, Morphine, Morphineone, Morphine-N-Oxide, Myorphine, Nalbuphine, Nicocodeine, Nicodicodeine, Nicomorphine, Norcodeine, Ohmefentanyl, Omnopon, Opium, Oxycodone, Oxymorphone, PEPAP, Pantopon, Papaveretum, Paregoric, Pentazocine, Pethidine(Meperidine), Phenadoxone, Phenazocine, Phenoperidine, Pholcodeine, Piminodine, Piritramide, Prodine, Proheptazine, Propiram, Propoxyphene, Racemethorphan, Racemorphan, Remifentanil, Sufentanil, Tetrapon, Thebacon, Tilidine, Tramadol, Trimeperidine |
| Salicylic acid and derivatives: Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide -- See also: NSAIDs | |
| Pyrazolones: |
Aminophenazone, Metamizole, Phenazone |
| Anilides: | |
| Others: |
Ziconotide, Tetrahydrocannabinol, Ibuprofen, Ketoprofen, Mefenamic Acid, Naproxen, Diclofenac, Flurbiprofen, Diflunisal, Fenoprofen, Indomethacin, Ketorolac; Meclofenamate, Meloxicam, Piroxicam, Tolmetin, |
