Perfluorocarbon

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Perfluorocarbons(or PFCs) are compounds derived from hydrocarbons by replacement of hydrogen atoms by fluorine atoms. PFC is 6500-9200 times more effective than carbon dioxide at trapping heat in the atmosphere [1], entirely non-toxic, and made up of atoms of carbon, fluorine, and/or sulfur.

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[edit] Medicine

Perfluorocarbons are commonly used in eye surgery as temporary replacements of the vitreous humor in retinal detachment surgery. The length of the perfluorated carbon chain determines the physical properties of a particular perfluorocarbon. Small chain perfluorocarbons, such as perfluoro-propane, are gases that rise inside the eye and seal retinal holes. Larger chain perfluorocarbons, such as perfluoro-octane, are liquids heavier than water and are used in surgery to immobilize an infolded retina.

Perfluorocarbons are also used in contrast enhanced ultrasound to improve ultrasound signal backscatter. The perfluorocarbons used in the microbubbles of some ultrasound contrast media are liquids at room temperature, but gases at body temperature. The gas-filled microbubbles oscillate and vibrate when a sonic energy field is applied and characteristically reflect ultrasound waves. This distinguishes the microbubbles from surrounding tissues.

Their stability, inertness, low diffusion rate and solubility increase the duration of contrast enhancement as compared to microbubbles containing air. PFC is also being used in artificial blood and liquid breathing. The theory behind liquid breathing is that, since perfluorocarbons carry oxygen so well, a given person should be able to jump into a pool full of perfluorocarbons and breathe as if he or she were breathing air.

[edit] Industry and the environment

PFC is being used in refrigerating units and "clean" fire extinguishers. However PFCs are hugely potent greenhouse gases and they are a long-term problem with a lifetime up to 50,000 years (PMID 14572085). In a 2003 study, the most abundant atmospheric PFC was tetrafluoromethane (PMID 14572085). Several governments concerned about the properties of PFCs have already tried to implement international agreements to limit their usage before it becomes a future global warming issue. PFCs are one of the classes of compounds regulated in the Kyoto Protocol.

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