Percutaneous aortic valve replacement

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In Percutaneous Aortic Valve Replacement (PAVR), a synthetic valve is transported to the heart through an small hole made in groin. This procedure can be compared to that performed when placing a stent, or performing balloon angioplasty.

Aortic valve replacement is an invasive procedure, with considerable mortality and morbidity, especially in more fragile patients. As of 2005, trials are being performed in which the dysfunctional aortic valve is replaced percutaneously, which removes the need for open heart surgery.

As of late 2006, this procedure is experimental, but initial results are encouraging. ^[1]

[edit] References

1. ^ Grube E, Laborde J, Gerckens U, Felderhoff T, Sauren B, Buellesfeld L, Mueller R, Menichelli M, Schmidt T, Zickmann B, Iversen S, Stone G (2006). "Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease: the Siegburg first-in-man study.". Circulation 114 (15): 1616-24. PMID 17015786.

[edit] Further reading

• van Herwerden L, Serruys P (2002). "Percutaneous valve implantation: back to the future?". Eur Heart J 23 (18): 1415-6. PMID 12208220.

• de Jaegere, Peter; Arie Pieter Kappetein; Marco Knook; Ben Ilmer; Dries van der Woerd; Yvon Deryck; Marjo de Ronde; Ricardo Boks; G. Sianos; Jurgen Ligthart; Jean-Claude Laborde; Ad Bogers; Patrick W. Serruys. "Percutaneous aortic valve replacement in a patient who could not undergo surgical treatment. A case report with the CoreValve aortic valve prosthesis.". ', 1:475-479. Retrieved on 18 October 2006.