Palladin
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| The eukaryotic cytoskeleton. Palladin is one component of this complex cellular machinery. | |
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Palladin
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| Identifiers | |
| Symbol(s) | [1] |
| Entrez | 23240 |
| RefSeq | NM_015196 |
| UniProt | [2] |
| Other data | |
| Locus | Chr. 4 q32-33 |
Palladin protein is a cytoskeletal protein coded by the palladin gene (KIAA0992).
Recently, it has been demonstrated that palladin RNA is overexpressed in patients with pancreatic neoplasia, and that the overexpression due to a mutation in palladin is inheritable. [1] More research is required before this protein and its role in neoplasia can be fully understood.
[edit] References
- ^ Kay L. Pogue-Geile, Ru Chen, Mary P. Bronner, Tatjana Crnogorac-Jurcevic, Kara White Moyes, Sally Dowen, Carol A. Otey, David A. Crispin, Ryan D. George, David C. Whitcomb, Teresa A. Brentnall. "Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism". PLoS Medicine 3 (12): 1-13.
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