Nicotiana rustica
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 Nicotiana rustica
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Nicotiana rustica, known in South America as Mapacho, is a very potent variety of tobacco. The high concentration of nicotine in its leaves makes it useful for creating organic pesticides.
Rustica is also used for entheogenic purposes by South American shamans. Growing in the rainforest it contains up to twenty times more nicotine than common North American varieties such as N. tabacum. Most commonly, it is allowed to soak in water, and the water is then insufflated; it is also smoked in cigars and used as an enema. It is also a common admixture of Ayahuasca in some parts of the rainforest. Great care should be taken in its use since nicotine is a deadly poison in even small doses.[1]
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