Naringin

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Naringin
Systematic name	7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D- glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy- 2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Other names	Naringin 4',5,7-Trihydroxyflavanone-7-rhamnoglucoside 4',5,7-Trihydroxyflavanone-7-rutinoside
Chemical formula	C27H32O14
Molecular mass	580.541 g/mol
Density	? g/cm3
Melting point	166 °C
CAS number	[10236-47-2]
SMILES	OC(C=C3)=CC=[C@@]3[C@@H]2CC(C1=C(O) C=C(O[C@H]4[C@H](O[C@]5([H])O[C@@H] (C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O) [C@H](O)[C@@H](CO)O4)C=C1O2)=O
Disclaimer and references

Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavonone naringenin in humans. Both naringin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits.

[edit] Activity

Narinigin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid-lowering, anticarcinogenic activity, and inhibition of selected cytochrome P450 enzymes including CYP3A4 and CYP1A2, which may result in several drug interactions in-vitro. ^[1]

[edit] References

1. ^ Grapefruit Juice and Medications

[edit] External links

• Links to external chemical sources.