Nabilone

From Wikipedia, the free encyclopedia

Nabilone
Systematic (IUPAC) name
?
Identifiers
CAS number	51022-71-0
ATC code	A04AD11
PubChem	5284592
DrugBank	APRD01127
Chemical data
Formula	C24H36O3
Mol. weight	372.541 g/mol
Pharmacokinetic data
Bioavailability	20% after first-pass by the liver
Metabolism	?
Half life	2 hours, with metabolites around 35 hours.
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Nabilone is a cannabinoid with therapeutic uses. It is an analog of dronabinol (also known as tetrahydrocannabinol or THC), the psychoactive ingredient in cannabis[1]. In Canada, the United States, and the United Kingdom, nabilone is marketed as Cesamet.

Nabilone is a racemate consisting of the (S,S) and the (R,R) isomers ("trans").

[edit] References

• Compounds That Bind to Cannabinoid Receptors, Table 2.2, Marijuana and Medicine: Assessing the Science Base, Institute of Medicine.