N-Acetylglutamate synthase
From Wikipedia, the free encyclopedia
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N-Acetylglutamate synthase
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| Identifiers | |
| Symbol(s) | NAGS |
| Entrez | 162417 |
| OMIM | 608300 |
| RefSeq | NM_153006 |
| UniProt | Q8N159 |
| Other data | |
| Locus | Chr. 17 q21.31 |
N-acetylglutamate synthase is an enzyme which catalyses the production of N-acetylglutamate from acetyl-CoA and glutamate. This enzyme is important in bacteria and plants for the synthesis of arginine, because it is part of this pathway, also this enzyme is important for mammals, because it produces the regulator of urea cycle N-acetylglutamate, which activates carbamoyl phosphate synthetase I, which catalyses the initial reactions of urea cycle.
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[edit] References
- Lehninger principles of biochemistry, 4th edition, David L. Nelson, Michael M. Cox
