Mitragynine

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Mitragynine
Systematic name	Mitragynine
Chemical formula	C23H30N2O4
Molecular mass	398.2206 g/mol
Density	x.xxx g/cm³
Melting point	39 - 41 °C
Melting point of HCl Salt	117.22 °C
Boiling point	110 - 115.6 °C
CAS number	[xx-xx-xx]
SMILES	xxxxx
Disclaimer and references

Mitragynine, an indole, is the primary active alkaloid in the plant mitragyna speciosa, commonly known as Kratom. On small doses its activity is reported to be stimulant like, while in higher doses more opiate like. Its potential for treating drug addiction, perhaps in combination with ibogaine, is being investigated.

Mitragynine was isolated in 1907 by D. Hooper, a process repeated in 1921 by E. Field who gave the alkaloid its name. Its structure was first fully determined in 1964 by D. Zacharias, R. Rosenstein and E. Jeffrey.

It is structurally related to both the yohimbe alkaloids and voacangine. It is more distantly related to other tryptamine-based psychedelic drugs such as psilocybin or LSD. Chemically, mitragynine is 9-methoxy-corynantheidine.

[edit] Chemical traits

Physically the freebase is a white, amorphous powder. It is soluble in alcohol, chloroform and acetic acid.

[edit] References

• Takayama H.; Maeda M.; Ohbayashi S.; Kitajima M.; Sakai S.-i.; Aimi N. (1995). "The First Total Synthesis of (-)-Mitragynine, An Analgesic Indole Alkaloid in Mitragyna speciosa". Tetrahedron Letters 36 (51): 9337-9340. DOI:10.1016/0040-4039(95)02022-H.