MIDIbox
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The MIDIbox project is an open source hardware and software MIDI platform built around the PIC18F(452) family of PIC microcontrollers. The MIDIbox Hardware Platform (MBHP) consists of a Core Module with midi interface that can be extended by a vast variety of I/O modules — and a MIDIbox operating system (MIOS) that can be customized by anyone able to read the documentation. MIOS supports programs written in C and/or Assembler. Programs can be uploaded by MIDI.
MIDIbox, like many open source projects, has a dedicated user community. Kits and PCBs are available.