Mevastatin
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Mevastatin
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| Systematic (IUPAC) name | |
| Compactin | |
| Identifiers | |
| CAS number | 73573-88-3 |
| ATC code | ? |
| PubChem | 64715 |
| DrugBank | EXPT00012 |
| Chemical data | |
| Formula | C23H36O6 |
| Mol. weight | 408.534 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Mevastatin, compactin, ML-236B is a hypolipidemic agent that belongs to the statins class.
It was the first compound isolated in the 70s during research into HMG-CoA reductase inhibitors produced by a mould Penicillium citrinum.
Mevastatin is not used in therapy of hyperlipidemias because of multiple side effects but it is the only source for production of other statin - pravastatin.
[edit] External links
| Statins (C10AA) edit | ||
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Atorvastatin, Cerivastatin, Fluvastatin, Lovastatin, Mevastatin, Pitavastatin, Pravastatin, Rosuvastatin, Simvastatin |
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